Download MendeleyThe structure of human GPX8
Kavanagh, K.L., Johansson, C., Yue, W.W., Kochan, G., Oppermann, U.To be published.
3CYN
The structure of human GPX8
- PDB DOI: https://doi.org/10.2210/pdb3CYN/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2008-04-25 Released: 2008-08-12
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.199
- R-Value Work: 0.171
- R-Value Observed: 0.172
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Probable glutathione peroxidase 8 | 189 | Homo sapiens | Mutation(s): 0 Gene Names: LOC493869 EC: 1.11.1.9 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8TED1 (Homo sapiens) Explore Q8TED1 Go to UniProtKB: Q8TED1 | |||||
PHAROS: Q8TED1 GTEx: ENSG00000164294 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8TED1 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | D [auth A] F [auth B] G [auth B] H [auth B] I [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| GOL Query on GOL | E [auth A], J [auth B], L [auth C] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.199
- R-Value Work: 0.171
- R-Value Observed: 0.172
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 90.688 | α = 90 |
| b = 120.854 | β = 119.38 |
| c = 75.603 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MAR345 | data collection |
| MOSFLM | data reduction |
| SCALA | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2008-08-12 Deposition Author(s): Kavanagh, K.L., Johansson, C., Yue, W.W., Kochan, G., Pike, A.C.W., Murray, J., Roos, A.K., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Wikstrom, M., Edwards, A.M., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2008-08-12
Type: Initial release - Version 1.1: 2011-07-13
Changes: Advisory, Version format compliance - Version 1.2: 2017-10-25
Changes: Refinement description, Source and taxonomy - Version 1.3: 2018-01-31
Changes: Structure summary - Version 1.4: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
