3CAF

Crystal Structure of hFGFR2 D2 Domain

PDB DOI: https://doi.org/10.2210/pdb3CAF/pdb

Classification: TRANSFERASE
Organism(s): Homo sapiens
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2008-02-19 Released: 2009-01-27
Deposition Author(s): Guo, F., Dakshinamurthy, R., Kathir, K.M., Thallapuranam, S.K.K., Sakon, J.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 1.96 Å
R-Value Free: 0.275
R-Value Work: 0.187
R-Value Observed: 0.191

wwPDB Validation 3D Report Full Report

This is version 1.1 of the entry. See complete history.

Literature

Crystal structure analysis of the hFGFR2 D2 domain

Guo, F., Dakshinamurthy, R., Kathir, K.M., Thallapuranam, S.K.K., Sakon, J.

To be published.

Macromolecule Content

Total Structure Weight: 11.61 kDa
Atom Count: 868
Modelled Residue Count: 100
Deposited Residue Count: 100
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Fibroblast growth factor receptor 2	A	100	Homo sapiens	Mutation(s): 0 Gene Names: FGFR2, BEK, KGFR, KSAM EC: 2.7.10.1
UniProt & NIH Common Fund Data Resources
Find proteins for P21802 (Homo sapiens) Explore P21802 Go to UniProtKB: P21802
PHAROS: P21802 GTEx: ENSG00000066468
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P21802
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 1.96 Å
R-Value Free: 0.275
R-Value Work: 0.187
R-Value Observed: 0.191
Space Group: P 2₁ 2₁ 2

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 42.5	α = 90
b = 79.9	β = 90
c = 37.29	γ = 90

Software Package:

Software Name	Purpose
d*TREK	data scaling
PHASER	phasing
REFMAC	refinement
PDB_EXTRACT	data extraction
CrystalClear	data collection
CrystalClear	data reduction
CrystalClear	data scaling

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2009-01-27

Deposition Author(s):

Dakshinamurthy, R.

Thallapuranam, S.K.K.

Revision History (Full details and data files)

Version 1.0: 2009-01-27
Type: Initial release
Version 1.1: 2011-07-13
Changes: Advisory, Version format compliance

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.