3AQQ

Crystal structure of human CRHSP-24

PDB DOI: https://doi.org/10.2210/pdb3AQQ/pdb

Classification: DNA BINDING PROTEIN
Organism(s): Homo sapiens
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2010-11-17 Released: 2010-12-22
Deposition Author(s): Hou, H., Wang, F., Zhang, W., Wang, D., Li, X., Bartlam, M., Yao, X., Rao, Z.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.80 Å
R-Value Free: 0.272
R-Value Work: 0.229
R-Value Observed: 0.231

wwPDB Validation 3D Report Full Report

This is version 1.1 of the entry. See complete history.

Literature

CRHSP-24 is a novel cargo adaptor trafficking between stress granules and processing bodies

Hou, H., Wang, F., Zhang, W., Wang, D., Li, X., Bartlam, M., Yao, X., Rao, Z.

To be published.

Macromolecule Content

Total Structure Weight: 63.66 kDa
Atom Count: 3,048
Modelled Residue Count: 393
Deposited Residue Count: 588
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Calcium-regulated heat stable protein 1	A, B [auth C], C [auth B], D	147	Homo sapiens	Mutation(s): 0 Gene Names: CARHSP1
UniProt & NIH Common Fund Data Resources
Find proteins for Q9Y2V2 (Homo sapiens) Explore Q9Y2V2 Go to UniProtKB: Q9Y2V2
PHAROS: Q9Y2V2 GTEx: ENSG00000153048
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q9Y2V2
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 2.80 Å
R-Value Free: 0.272
R-Value Work: 0.229
R-Value Observed: 0.231
Space Group: P 6₁

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 79.856	α = 90
b = 79.856	β = 90
c = 181.982	γ = 120

Software Package:

Software Name	Purpose
ADSC	data collection
PHENIX	model building
PHENIX	refinement
HKL-2000	data reduction
HKL-2000	data scaling
PHENIX	phasing

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2010-12-22

Deposition Author(s):

Revision History (Full details and data files)

Version 1.0: 2010-12-22
Type: Initial release
Version 1.1: 2011-07-13
Changes: Version format compliance

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.