Download MendeleyCrystal structures of human and rat intestinal fatty acid binding protein in complex with 11-(Dansylamino)undecanoic acid
Laguerre, A.J.K., Wielens, J., Parker, M.W., Porter, C.J., Scanlon, M.J.To be published.
3AKN
X-ray structure of iFABP from human and rat with bound fluorescent fatty acid analogue
- PDB DOI: https://doi.org/10.2210/pdb3AKN/pdb
- Classification: TRANSPORT PROTEIN
- Organism(s): Rattus norvegicus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2010-07-14 Released: 2011-07-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 Å
- R-Value Free: 0.257
- R-Value Work: 0.225
- R-Value Observed: 0.226
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Fatty acid-binding protein, intestinal | 131 | Rattus norvegicus | Mutation(s): 0 Gene Names: Fabp2, Fabpi |  | |
UniProt | |||||
Find proteins for P02693 (Rattus norvegicus) Explore P02693 Go to UniProtKB: P02693 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P02693 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 11D Query on 11D | B [auth A] | 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid C23 H34 N2 O4 S CEPGVMDMVJGHFQ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 Å
- R-Value Free: 0.257
- R-Value Work: 0.225
- R-Value Observed: 0.226
- Space Group: P 43 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 50.59 | α = 90 |
| b = 50.59 | β = 90 |
| c = 97.452 | γ = 90 |
| Software Name | Purpose |
|---|---|
| Blu-Ice | data collection |
| AMoRE | phasing |
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
Entry History
Deposition Data
- Released Date: 2011-07-20 Deposition Author(s): Wielens, J., Laguerre, A.J.K., Parker, M.W., Scanlon, M.J.
Revision History (Full details and data files)
- Version 1.0: 2011-07-20
Type: Initial release - Version 1.1: 2023-11-01
Changes: Data collection, Database references, Derived calculations, Refinement description
