Download MendeleyCrystal structure of a novel HIV fusion inhibitor
Yao, X., Waltersperger, S., Wang, M., Cui, S.To be published.
3VTQ
Novel HIV fusion inhibitor
- PDB DOI: https://doi.org/10.2210/pdb3VTQ/pdb
- Classification: VIRAL PROTEIN/ANTIVIRAL PROTEIN
- Organism(s): Human immunodeficiency virus 1
- Mutation(s): Yes
- Deposited: 2012-06-02 Released: 2013-06-26
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.53 Å
- R-Value Free: 0.218
- R-Value Work: 0.196
- R-Value Observed: 0.197
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Envelope glycoprotein gp160 | A [auth E], B [auth A], C [auth B] | 38 | Human immunodeficiency virus 1 | Mutation(s): 2 |  |
UniProt | |||||
Find proteins for Q9YP39 (Human immunodeficiency virus 1) Explore Q9YP39 Go to UniProtKB: Q9YP39 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9YP39 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| fusion inhibitor MT-Sifuvirtide | D, E [auth C], F | 39 | N/A | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.53 Å
- R-Value Free: 0.218
- R-Value Work: 0.196
- R-Value Observed: 0.197
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 41.99 | α = 90 |
| b = 47.858 | β = 90 |
| c = 109.891 | γ = 90 |
| Software Name | Purpose |
|---|---|
| RemDAq | data collection |
| PHASER | phasing |
| PHENIX | refinement |
| XDS | data reduction |
| XDS | data scaling |
Entry History
Deposition Data
- Released Date: 2013-06-26 Deposition Author(s): Yao, X., Waltersperger, S., Wang, M., Cui, S.
Revision History (Full details and data files)
- Version 1.0: 2013-06-26
Type: Initial release - Version 1.1: 2023-11-08
Changes: Data collection, Database references, Derived calculations, Refinement description
