Download MendeleyMethionine-adenosyltransferase from Entamoeba histolytica
Merritt, E.A., Arakaki, T., Zhang, L., Napuli, A., Van Voorhis, W.C., Buckner, F.S., Fan, E., Zucker, F., Verlinde, C.L.M.J., Hol, W.G.J.To be published.
3SO4
Methionine-adenosyltransferase from Entamoeba histolytica
- PDB DOI: https://doi.org/10.2210/pdb3SO4/pdb
- Classification: TRANSFERASE
- Organism(s): Entamoeba histolytica
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2011-06-29 Released: 2011-07-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.18 Å
- R-Value Free: 0.284
- R-Value Work: 0.228
- R-Value Observed: 0.231
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Methionine-adenosyltransferase | 415 | Entamoeba histolytica | Mutation(s): 0 Gene Names: 103.m00148, EHI_174250 EC: 2.5.1.6 |  | |
UniProt | |||||
Find proteins for C4M272 (Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)) Explore C4M272 Go to UniProtKB: C4M272 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | C4M272 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ACT Query on ACT | E [auth A], F [auth B], G [auth C], H [auth D] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.18 Å
- R-Value Free: 0.284
- R-Value Work: 0.228
- R-Value Observed: 0.231
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 58.492 | α = 90 |
| b = 113.161 | β = 90 |
| c = 220.848 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| Blu-Ice | data collection |
| HKL-2000 | data reduction |
| BALBES | phasing |
Entry History
Deposition Data
- Released Date: 2011-07-20 Deposition Author(s): Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Revision History (Full details and data files)
- Version 1.0: 2011-07-20
Type: Initial release - Version 1.1: 2017-11-08
Changes: Refinement description - Version 1.2: 2024-02-28
Changes: Data collection, Database references, Derived calculations
