Download MendeleyCrystal structures of human IGA1 and IGG1 fab fragments sharing the same variable domains
Trajtenberg, F., Correa-Bove, A., Pritsch, O., Dighiero, G., Oppezzo, P., Buschiazzo, A.To be published.
3QO0
Monoclinic form of IgG1 Fab fragment (in complex with antigenic peptide) sharing same Fv as IgA
- PDB DOI: https://doi.org/10.2210/pdb3QO0/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Homo sapiens
- Mutation(s): No
- Deposited: 2011-02-09 Released: 2012-02-15
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.221
- R-Value Work: 0.169
- R-Value Observed: 0.171
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN | 219 | Homo sapiens | Mutation(s): 0 |  | |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN | 220 | Homo sapiens | Mutation(s): 0 |  | |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by: Sequence | 3D Structure
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Peptide from Tubulin beta chain | 20 | N/A | Mutation(s): 0 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P07437 (Homo sapiens) Explore P07437 Go to UniProtKB: P07437 | |||||
PHAROS: P07437 GTEx: ENSG00000196230 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P07437 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GOL Query on GOL | D [auth A], E [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.221
- R-Value Work: 0.169
- R-Value Observed: 0.171
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 53.32 | α = 90 |
| b = 67.27 | β = 103.1 |
| c = 68.88 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SCALA | data scaling |
| BUSTER-TNT | refinement |
| PDB_EXTRACT | data extraction |
| MAR345dtb | data collection |
| XDS | data reduction |
| FFT | phasing |
| BUSTER | refinement |
Entry History
Deposition Data
- Released Date: 2012-02-15 Deposition Author(s): Trajtenberg, F., Correa-Bove, A., Buschiazzo, A.
Revision History (Full details and data files)
- Version 1.0: 2012-02-15
Type: Initial release - Version 1.1: 2017-11-08
Changes: Refinement description
