3Q0H

Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.70 Å
  • R-Value Free: 0.237 
  • R-Value Work: 0.207 
  • R-Value Observed: 0.209 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history


Literature

Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)

Ramagopal, U.A.Guo, H.Samanta, D.Nathenson, S.G.Almo, S.C.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
T cell immunoreceptor with Ig and ITIM domains
A, B
117Homo sapiensMutation(s): 0 
Gene Names: TIGITVSIG9VSTM3
UniProt & NIH Common Fund Data Resources
Find proteins for Q495A1 (Homo sapiens)
Explore Q495A1 
Go to UniProtKB:  Q495A1
PHAROS:  Q495A1
GTEx:  ENSG00000181847 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ495A1
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.70 Å
  • R-Value Free: 0.237 
  • R-Value Work: 0.207 
  • R-Value Observed: 0.209 
  • Space Group: P 1 21 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 39.951α = 90
b = 74.671β = 92.39
c = 43.346γ = 90
Software Package:
Software NamePurpose
SCALEPACKdata scaling
REFMACrefinement
PDB_EXTRACTdata extraction
CBASSdata collection
HKL-2000data reduction
PHASERphasing

Structure Validation

View Full Validation Report



Entry History 

Revision History  (Full details and data files)

  • Version 1.0: 2011-02-16
    Type: Initial release
  • Version 1.1: 2011-07-13
    Changes: Version format compliance
  • Version 1.2: 2017-11-08
    Changes: Refinement description
  • Version 1.3: 2023-09-13
    Changes: Data collection, Database references, Refinement description