3OYW
Crystal structure of human galectin-1 in complex with thiodigalactoside
- PDB DOI: https://doi.org/10.2210/pdb3OYW/pdb
- Classification: CARBOHYDRATE BINDING PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No 
- Deposited: 2010-09-23 Released: 2010-11-03 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.245 
- R-Value Work: 0.167 
- R-Value Observed: 0.171 
wwPDB Validation   3D Report Full Report
This is version 3.0 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Galectin-1 | 134 | Homo sapiens | Mutation(s): 0  Gene Names: LGALS1 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P09382 (Homo sapiens) Explore P09382  Go to UniProtKB:  P09382 | |||||
PHAROS:  P09382 GTEx:  ENSG00000100097  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P09382 | ||||
Sequence AnnotationsExpand | |||||
|
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Galectin-1 | 134 | Homo sapiens | Mutation(s): 0  Gene Names: LGALS1 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P09382 (Homo sapiens) Explore P09382  Go to UniProtKB:  P09382 | |||||
PHAROS:  P09382 GTEx:  ENSG00000100097  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P09382 | ||||
Sequence AnnotationsExpand | |||||
|
Oligosaccharides
Small Molecules
Modified Residues 2 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Type | Formula | 2D Diagram | Parent |
CME Query on CME | A | L-PEPTIDE LINKING | C5 H11 N O3 S2 | CYS | |
CSO Query on CSO | A | L-PEPTIDE LINKING | C3 H7 N O3 S | CYS |
Biologically Interesting Molecules (External Reference) 1 Unique
Entity ID: 3 | |||||
---|---|---|---|---|---|
ID | Chains | Name | Type/Class | 2D Diagram | 3D Interactions |
PRD_900027 Query on PRD_900027 | C [auth E], D [auth F] | thiodigalactoside | Oligosaccharide / Substrate analog |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.245 
- R-Value Work: 0.167 
- R-Value Observed: 0.171 
- Space Group: P 21 21 21
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 44.368 | α = 90 |
b = 58.367 | β = 90 |
c = 111.793 | γ = 90 |
Software Name | Purpose |
---|---|
PROTEUM PLUS | data collection |
REFMAC | refinement |
SAINT | data reduction |
SCALA | data scaling |
Entry History 
Deposition Data
- Released Date: 2010-11-03  Deposition Author(s): Blanchard, H., Collins, P.M.
Revision History (Full details and data files)
- Version 1.0: 2010-11-03
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2017-11-08
Changes: Refinement description - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Derived calculations, Non-polymer description, Structure summary - Version 3.0: 2020-08-12
Changes: Atomic model, Data collection, Derived calculations, Structure summary