3MXJ

Crystal Structure of the mTREX1 Apoprotein

PDB DOI: https://doi.org/10.2210/pdb3MXJ/pdb

Classification: HYDROLASE
Organism(s): Mus musculus
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2010-05-07 Released: 2011-05-18
Deposition Author(s): Bailey, S.L., Hollis, T.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 1.95 Å
R-Value Free: 0.237
R-Value Work: 0.204
R-Value Observed: 0.205

wwPDB Validation 3D Report Full Report

This is version 1.2 of the entry. See complete history.

Literature

X-ray Crystal Structures of TREX1 3' Exonuclease Autoimmune Disease Mutants

Bailey, S.L., Harvey, S., Perrino, F.W., Hollis, T.

To be published.

Macromolecule Content

Total Structure Weight: 52.65 kDa
Atom Count: 3,556
Modelled Residue Count: 429
Deposited Residue Count: 484
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Three prime repair exonuclease 1	A [auth B], B [auth A]	242	Mus musculus	Mutation(s): 0 Gene Names: Trex1 EC: 3.1.11.2
UniProt
Find proteins for Q91XB0 (Mus musculus) Explore Q91XB0 Go to UniProtKB: Q91XB0
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q91XB0
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 1.95 Å
R-Value Free: 0.237
R-Value Work: 0.204
R-Value Observed: 0.205
Space Group: P 2₁ 2₁ 2₁

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 64.16	α = 90
b = 85.72	β = 90
c = 100.27	γ = 90

Software Package:

Software Name	Purpose
CrystalClear	data collection
PHASER	phasing
PHENIX	refinement
d*TREK	data reduction
d*TREK	data scaling

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2011-05-18

Deposition Author(s):

Revision History (Full details and data files)

Version 1.0: 2011-05-18
Type: Initial release
Version 1.1: 2011-07-13
Changes: Version format compliance
Version 1.2: 2024-02-21
Changes: Data collection, Database references

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.