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CONFORMATIONAL CHANGES IN THE (ALA-84-VAL) MUTANT OF TUMOR NECROSIS FACTOR
2TUN
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Lymphokine
    Structure Weight: 104381.41
    Molecule: TUMOR NECROSIS FACTOR-ALPHA
    Polymer: 1 Type: protein Length: 157
    Chains: A, B, C, D, E, F
    Mutation: A84V
    Organism: Homo sapiens
    Gene Names: Gene View for TNF TNFA TNFSF2
    UniProtKB: Protein Feature View | Search PDB | P01375  
     
  •   Structure Validation Hide

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  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human  
     
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  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PQS (software)
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  •   Deposition Summary Hide
    Authors:   Saludjian, P.,  Prange, T.

    Deposition:   1993-10-06
    Release:   1994-01-31
    Last Modified (REVDAT):   2013-06-19
     
  •   Revision History    Hide
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    2013-06-19
    Other
    2011-07-13
    Biological assembly
    2011-07-13
    Version format compliance
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   3.10
    R-Value: 0.198 (obs.)
    R-Free: n/a
    Space Group: P 31 2 1
    Unit Cell:
      Length [Å] Angles [°]
    a = 166.00 α = 90.00 
    b = 166.00 β = 90.00 
    c = 93.70 γ = 120.00