Download MendeleyOn the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Walter, J., Steigemann, W., Singh, T.P., Bartunik, H., Bode, W., Huber, R.(1982) Acta Crystallogr B 38: 1462-1472
2TPI
ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
- PDB DOI: https://doi.org/10.2210/pdb2TPI/pdb
- Classification: Hydrolase/hydrolase INHIBITOR
- Organism(s): Bos taurus
- Mutation(s): No
- Deposited: 1981-10-26 Released: 1982-03-04
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.10 Å
- R-Value Work: 0.200
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| TRYPSINOGEN | A [auth Z] | 229 | Bos taurus | Mutation(s): 0 Gene Names: PRSS1 EC: 3.4.21.4 |  |
UniProt | |||||
Find proteins for P00760 (Bos taurus) Explore P00760 Go to UniProtKB: P00760 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00760 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| TRYPSIN INHIBITOR | B [auth I] | 58 | Bos taurus | Mutation(s): 0 |  |
UniProt | |||||
Find proteins for P00974 (Bos taurus) Explore P00974 Go to UniProtKB: P00974 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00974 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| HG Query on HG | E [auth Z] | MERCURY (II) ION Hg BQPIGGFYSBELGY-UHFFFAOYSA-N |  | ||
| ILE Query on ILE | C [auth Z] | ISOLEUCINE C6 H13 N O2 AGPKZVBTJJNPAG-WHFBIAKZSA-N |  | ||
| VAL Query on VAL | D [auth Z] | VALINE C5 H11 N O2 KZSNJWFQEVHDMF-BYPYZUCNSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.10 Å
- R-Value Work: 0.200
- Space Group: I 2 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 75.67 | α = 90 |
| b = 84.16 | β = 90 |
| c = 122.89 | γ = 90 |
Entry History
Deposition Data
- Released Date: 1982-03-04 Deposition Author(s): Walter, J., Steigemann, W., Singh, T.P., Bartunik, H., Bode, W., Huber, R.
Revision History (Full details and data files)
- Version 1.0: 1982-03-04
Type: Initial release - Version 1.1: 2008-03-03
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance
