2RU1

Solution structure of esf3


Experimental Data Snapshot

  • Method: SOLUTION NMR
  • Conformers Calculated: 100 
  • Conformers Submitted: 20 
  • Selection Criteria: target function 

wwPDB Validation   3D Report Full Report


This is version 1.1 of the entry. See complete history


Literature

Central cell-derived peptides regulate early embryo patterning in flowering plants

Costa, L.M.Marshall, E.Tesfaye, M.Silverstein, K.A.Mori, M.Umetsu, Y.Otterbach, S.L.Papareddy, R.Dickinson, H.G.Boutiller, K.Vandenbosch, K.A.Ohki, S.Gutierrez-marcos, J.F.

(2014) Science 344: 168-172

  • DOI: https://doi.org/10.1126/science.1243005
  • Primary Citation of Related Structures:  
    2RU1

  • PubMed Abstract: 

    Plant embryogenesis initiates with the establishment of an apical-basal axis; however, the molecular mechanisms accompanying this early event remain unclear. Here, we show that a small cysteine-rich peptide family is required for formation of the zygotic basal cell lineage and proembryo patterning in Arabidopsis. EMBRYO SURROUNDING FACTOR 1 (ESF1) peptides accumulate before fertilization in central cell gametes and thereafter in embryo-surrounding endosperm cells. Biochemical and structural analyses revealed cleavage of ESF1 propeptides to form biologically active mature peptides. Further, these peptides act in a non-cell-autonomous manner and synergistically with the receptor-like kinase SHORT SUSPENSOR to promote suspensor elongation through the YODA mitogen-activated protein kinase pathway. Our findings demonstrate that the second female gamete and its sexually derived endosperm regulate early embryonic patterning in flowering plants.


  • Organizational Affiliation

    Department of Plant Sciences, University of Oxford, South Parks Road, OX1 3RB, UK.


Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Uncharacterized protein70Arabidopsis thalianaMutation(s): 0 
Gene Names: AT1G10717At1g10717
UniProt
Find proteins for A8MQA5 (Arabidopsis thaliana)
Explore A8MQA5 
Go to UniProtKB:  A8MQA5
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupA8MQA5
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: SOLUTION NMR
  • Conformers Calculated: 100 
  • Conformers Submitted: 20 
  • Selection Criteria: target function 

Structure Validation

View Full Validation Report



Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2014-04-23
    Type: Initial release
  • Version 1.1: 2023-06-14
    Changes: Data collection, Database references, Other