2RF0

Crystal structure of human mixed lineage kinase MAP3K10 SH3 domain


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.00 Å
  • R-Value Free: 0.230 
  • R-Value Work: 0.189 
  • R-Value Observed: 0.191 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history


Literature

The crystal structure of human Mixed lineage kinase MAP3K10 SH3 domain.

Ugochukwu, E.Eswaran, J.Elkins, J.Keates, T.Pike, A.C.W.Berridge, G.Savitsky, P.Sundstrom, M.Arrowsmith, C.H.Weigelt, J.Edwards, A.M.von Delft, F.Knapp, S.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Mitogen-activated protein kinase kinase kinase 10
A, B, C, D
89Homo sapiensMutation(s): 0 
Gene Names: MAP3K10MLK2MST
EC: 2.7.11.25
UniProt & NIH Common Fund Data Resources
Find proteins for Q02779 (Homo sapiens)
Explore Q02779 
Go to UniProtKB:  Q02779
PHAROS:  Q02779
GTEx:  ENSG00000130758 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ02779
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.00 Å
  • R-Value Free: 0.230 
  • R-Value Work: 0.189 
  • R-Value Observed: 0.191 
  • Space Group: P 32 1 2
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 69.68α = 90
b = 69.68β = 90
c = 103.98γ = 120
Software Package:
Software NamePurpose
REFMACrefinement
MAR345data collection
MOSFLMdata reduction
SCALAdata scaling
PHASERphasing

Structure Validation

View Full Validation Report



Entry History 

Revision History  (Full details and data files)

  • Version 1.0: 2007-10-23
    Type: Initial release
  • Version 1.1: 2011-07-13
    Changes: Advisory, Version format compliance
  • Version 1.2: 2017-10-25
    Changes: Refinement description
  • Version 1.3: 2023-08-30
    Changes: Data collection, Database references, Refinement description