2Q9V

Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.00 Å
  • R-Value Free: 0.233 
  • R-Value Work: 0.167 
  • R-Value Observed: 0.170 

wwPDB Validation   3D Report Full Report


This is version 1.4 of the entry. See complete history


Literature

Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase.

Pilka, E.S.Hozjan, V.Kavanagh, K.L.Papagrigoriou, E.Cooper, C.Elkins, J.M.Doyle, D.A.von Delft, F.Sundstrom, M.Arrowsmith, C.A.Weigelt, J.Edwards, A.Oppermann, U.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 190Homo sapiensMutation(s): 1 
Gene Names: MAGI1BAIAP1BAP1TNRC19
UniProt & NIH Common Fund Data Resources
Find proteins for Q96QZ7 (Homo sapiens)
Explore Q96QZ7 
Go to UniProtKB:  Q96QZ7
PHAROS:  Q96QZ7
GTEx:  ENSG00000151276 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ96QZ7
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.00 Å
  • R-Value Free: 0.233 
  • R-Value Work: 0.167 
  • R-Value Observed: 0.170 
  • Space Group: P 21 21 21
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 32.821α = 90
b = 44.085β = 90
c = 54.512γ = 90
Software Package:
Software NamePurpose
REFMACrefinement
CrystalCleardata collection
MOSFLMdata reduction
SCALAdata scaling
PHASERphasing

Structure Validation

View Full Validation Report



Entry History 

Revision History  (Full details and data files)

  • Version 1.0: 2007-06-26
    Type: Initial release
  • Version 1.1: 2008-05-01
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Advisory, Version format compliance
  • Version 1.3: 2021-10-20
    Changes: Database references
  • Version 1.4: 2023-08-30
    Changes: Data collection, Refinement description