Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferrous heme and tryptophan. Northeast Structural Genomics Target XcR13.     DOI:10.2210/pdb2nw8/pdb

2NW8 Display Files close FASTA Sequence PDB File PDB File (Header) mmCIF File mmCIF File (Header) PDBML/XML File PDBML/XML File (Header) Download Files close FASTA Sequence PDB File (Text) PDB File (gz) mmCIF File mmCIF File (gz) PDBML/XML File PDBML/XML File (gz) Structure Factor (Text) Structure Factor (gz) Biological Assembly (gz) (A) Print this Page Share this Page close Email Delicious Stumble Google More... Link this Page

Primary Citation       Related Citations in PDB Entry (REMARK 1) Hide       Molecular Description Hide Classification: Oxidoreductase Structure Weight: 73214.93   Molecule: Tryptophan 2,3-dioxygenase Polymer: 1 Type: polypeptide(L) Length: 306 Chains: A, B       Source Hide Polymer: 1 Scientific Name: Xanthomonas campestris pv. campestris Expression System: Escherichia coli         Related PDB Entries Hide Id Details 1YW0  The same protein in apo form  1ZEE  Structural homolog in apo form  2NW7  The same protein in complex with ferric heme  2NW9  The same protein in complex with ferrous heme and 6-fluoro-L-tryptophan  2NWB  Structural homolog in complex with ferric heme        Ligand Chemical Component Hide Identifier Name Formula Interaction View HEM     PROTOPORPHYRIN IX CONTAINING FE C34 H32 Fe N4 O4 Ligand Explorer MN     MANGANESE (II) ION Mn Ligand Explorer TRP     TRYPTOPHAN C11 H12 N2 O2 Ligand Explorer       Derived Data Hide SCOP Classification v1.75 - (2 Domains) PFAM Classification - (2 Domains) GO Terms - (9 Terms)     Reset Layout

Biological Assembly     More Images... View in Jmol Other Viewers close KiNG WebMol QuickPDB FirstGlance Kiosk SimpleViewer Protein Workshop Ligand Explorer Biological assembly assigned by authors         Deposition Summary Hide Authors:   Forouhar, F.,   Anderson, J.L.R.,   Mowat, C.G.,   Bruckmann, C.,   Thackray, S.J.,   Seetharaman, J.,   Ho, C.K.,   Ma, L.C.,   Cunningham, K.,   Janjua, H.,   Zhao, L.,   Xiao, R.,   Liu, J.,   Baran, M.C.,   Acton, T.B.,   Rost, B.,   Montelione, G.T.,   Champman, S.K.,   Tong, L.,   Northeast Structural Genomics Consortium (NESG) Deposition:   2006-11-14 Release:   2006-12-19 Last Modified (REVDAT):   2009-02-24       Experimental Details Hide Method:   X-RAY DIFFRACTION Experimental Data:    [ EDS ] Resolution[Å]: 1.60 R-Value: 0.171 (obs.) R-Free: 0.189 Space Group: P 31 2 1 Unit Cell:   Length [Å] Angles [°] a = 114.09 α = 90.00  b = 114.09 β = 90.00  c = 96.23 γ = 120.00