Download MendeleyC-terminal helix folding upon pyrimidine-rich hairpin binding to PTB RRM1. Implications for PTB function in Encephalomyocarditis virus IRES activity.
Maris, C., Jayne, S.F., Damberger, F.F., Ravindranathan, S., Allain, F.H.-T.To be published.
2N3O
Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA
- PDB DOI: https://doi.org/10.2210/pdb2N3O/pdb
- BMRB: 25652
- NAKB: 2N3O
- Classification: RNA BINDING PROTEIN/RNA
- Organism(s): Homo sapiens, synthetic construct
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2015-06-08 Released: 2016-08-10
Experimental Data Snapshot
- Method: SOLUTION NMR
- Conformers Calculated: 250
- Conformers Submitted: 20
- Selection Criteria: structures with the least restraint violations
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Polypyrimidine tract-binding protein 1 | 123 | Homo sapiens | Mutation(s): 0 Gene Names: PTB, PTBP1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P26599 (Homo sapiens) Explore P26599 Go to UniProtKB: P26599 | |||||
PHAROS: P26599 GTEx: ENSG00000011304 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P26599 | ||||
Sequence AnnotationsExpand | |||||
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Find similar nucleic acids by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | Organism | Image | |
| RNA (5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3') | 23 | synthetic construct |  | ||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: SOLUTION NMR
- Conformers Calculated: 250
- Conformers Submitted: 20
- Selection Criteria: structures with the least restraint violations
Entry History
Deposition Data
- Released Date: 2016-08-10 Deposition Author(s): Maris, C., Jayne, S.F., Damberger, F.F., Ravindranathan, S., Allain, F.H.-T.
Revision History (Full details and data files)
- Version 1.0: 2016-08-10
Type: Initial release
