Download MendeleyStructural Basis for Discriminating or Non-Discriminating Functioning of Glutamyl-tRNA Synthetases
Bourenkov, G.P., Bruning, M., Strizhov, N., Shkolnaya, L.A., Bartunik, H.D.To be published.
2JA2
Mycobacterium tuberculosis glutamyl-tRNA synthetase
- PDB DOI: https://doi.org/10.2210/pdb2JA2/pdb
- Classification: LIGASE
- Organism(s): Mycobacterium tuberculosis H37Rv
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2006-11-20 Released: 2008-10-28
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.65 Å
- R-Value Free: 0.251
- R-Value Work: 0.206
- R-Value Observed: 0.208
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| GLUTAMYL-TRNA SYNTHETASE | 498 | Mycobacterium tuberculosis H37Rv | Mutation(s): 0 EC: 6.1.1.17 |  | |
UniProt | |||||
Find proteins for P9WFV9 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WFV9 Go to UniProtKB: P9WFV9 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P9WFV9 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ACT Query on ACT | B [auth A] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |  | ||
| CL Query on CL | C [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.65 Å
- R-Value Free: 0.251
- R-Value Work: 0.206
- R-Value Observed: 0.208
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 50.13 | α = 90 |
| b = 61.483 | β = 90 |
| c = 169.547 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2008-10-28 Deposition Author(s): Bourenkov, G.P., Strizhov, N., Shkolnaya, L.A., Bruning, M., Bartunik, H.D.
Revision History (Full details and data files)
- Version 1.0: 2008-10-28
Type: Initial release - Version 1.1: 2011-05-08
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2023-12-13
Changes: Data collection, Database references, Other, Refinement description
