Download MendeleyStructure of Human Calpain 13
Walker, J.R., Ng, K., Davis, T.L., Ravulapalli, R., Butler-Cole, C., Finerty Jr., P.J., Newman, E.M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.To be published.
2I7A
Domain IV of Human Calpain 13
- PDB DOI: https://doi.org/10.2210/pdb2I7A/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2006-08-30 Released: 2006-09-12
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.197
- R-Value Work: 0.169
- R-Value Observed: 0.171
wwPDB Validation 3D Report Full Report
This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Calpain 13 | 174 | Homo sapiens | Mutation(s): 0 Gene Names: CAPN13 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q6MZZ7 (Homo sapiens) Explore Q6MZZ7 Go to UniProtKB: Q6MZZ7 | |||||
PHAROS: Q6MZZ7 GTEx: ENSG00000162949 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q6MZZ7 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | C [auth A], D [auth A], E [auth A], F [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| GOL Query on GOL | G [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| CA Query on CA | B [auth A] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.197
- R-Value Work: 0.169
- R-Value Observed: 0.171
- Space Group: P 32 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 86.115 | α = 90 |
| b = 86.115 | β = 90 |
| c = 47.417 | γ = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| SBC-Collect | data collection |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2006-09-12 Deposition Author(s): Walker, J.R., Ng, K., Davis, T.L., Ravulapalli, R., Butler-cole, C., Finerty Jr., P.J., Newman, E.M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2006-09-12
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Derived calculations, Version format compliance - Version 1.3: 2017-10-18
Changes: Refinement description - Version 1.4: 2018-01-24
Changes: Structure summary - Version 1.5: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
