Download MendeleyCrystal structure of human glutathione peroxidase 5
Kavanagh, K.L., Oppermann, U.To be published.
2I3Y
Crystal structure of human glutathione peroxidase 5
- PDB DOI: https://doi.org/10.2210/pdb2I3Y/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2006-08-21 Released: 2006-09-12
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.228
- R-Value Work: 0.175
- R-Value Observed: 0.177
wwPDB Validation 3D Report Full Report
This is version 1.5 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Epididymal secretory glutathione peroxidase | 215 | Homo sapiens | Mutation(s): 0 Gene Names: GPX5 EC: 1.11.1.9 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O75715 (Homo sapiens) Explore O75715 Go to UniProtKB: O75715 | |||||
PHAROS: O75715 GTEx: ENSG00000224586 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O75715 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EDO Query on EDO | B [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.228
- R-Value Work: 0.175
- R-Value Observed: 0.177
- Space Group: P 62 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 104.544 | α = 90 |
| b = 104.544 | β = 90 |
| c = 71.663 | γ = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MAR345 | data collection |
| MOSFLM | data reduction |
| CCP4 | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2006-09-12 Deposition Author(s): Kavanagh, K.L., Johansson, C., Rojkova, A., Umeano, C., Bunkoczi, G., Gileadi, O., von Delft, F., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2006-09-12
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Advisory, Version format compliance - Version 1.3: 2017-10-18
Changes: Refinement description - Version 1.4: 2018-01-31
Changes: Structure summary - Version 1.5: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
