2G6Z

Crystal structure of human DUSP5

PDB DOI: https://doi.org/10.2210/pdb2G6Z/pdb

Classification: HYDROLASE
Organism(s): Homo sapiens
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2006-02-26 Released: 2007-01-16
Deposition Author(s): Kim, S.J., Ryu, S.E.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.70 Å
R-Value Free: 0.291
R-Value Work: 0.244
R-Value Observed: 0.248

wwPDB Validation 3D Report Full Report

This is version 1.2 of the entry. See complete history.

Literature

Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase

Jeong, D.G., Cho, Y.H., Yoon, T.S., Kim, J.H., Ryu, S.E., Kim, S.J.

(2007) Proteins 66: 253-258

PubMed: 17078075 Search on PubMed
DOI: https://doi.org/10.1002/prot.21224
Primary Citation of Related Structures:
2G6Z

Organizational Affiliation

Systemic Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, 52 Eoeun-Dong, Yuseong-Gu, Daejeon 305-333, Republic of Korea.

Macromolecule Content

Total Structure Weight: 70.05 kDa
Atom Count: 3,548
Modelled Residue Count: 436
Deposited Residue Count: 633
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Dual specificity protein phosphatase 5	A, B, C	211	Homo sapiens	Mutation(s): 0 EC: 3.1.3.48 (PDB Primary Data), 3.1.3.16 (PDB Primary Data)
UniProt & NIH Common Fund Data Resources
Find proteins for Q16690 (Homo sapiens) Explore Q16690 Go to UniProtKB: Q16690
PHAROS: Q16690 GTEx: ENSG00000138166
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q16690
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 1 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
SO4 Query on SO4 Download Ideal Coordinates CCD File SDF format, chain D [auth A] SDF format, chain E [auth A] SDF format, chain F [auth B] SDF format, chain G [auth B] SDF format, chain H [auth C] SDF format, chain I [auth C] MOL2 format, chain D [auth A] MOL2 format, chain E [auth A] MOL2 format, chain F [auth B] MOL2 format, chain G [auth B] MOL2 format, chain H [auth C] MOL2 format, chain I [auth C]	D [auth A] E [auth A] F [auth B] G [auth B] H [auth C] D [auth A], E [auth A], F [auth B], G [auth B], H [auth C], I [auth C]	SULFATE ION O₄ S QAOWNCQODCNURD-UHFFFAOYSA-L		Interactions Focus chain D [auth A] Focus chain E [auth A] Focus chain F [auth B] Focus chain G [auth B] Focus chain H [auth C] Focus chain I [auth C] Interactions & Density Focus chain D [auth A] Focus chain E [auth A] Focus chain F [auth B] Focus chain G [auth B] Focus chain H [auth C] Focus chain I [auth C]