Download MendeleyThe Crystal Structure of Human HMT1 hnRNP methyltransferase-like 3 in complex with SAH.
Wu, H., Min, J.R., Zeng, H., Loppnau, P., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N.To be published.
2FYT
Human HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae) protein
- PDB DOI: https://doi.org/10.2210/pdb2FYT/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2006-02-08 Released: 2006-03-14
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.246
- R-Value Work: 0.195
- R-Value Observed: 0.198
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Protein arginine N-methyltransferase 3 | 340 | Homo sapiens | Mutation(s): 0 Gene Names: HRMT1L3, PRMT3 EC: 2.1.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O60678 (Homo sapiens) Explore O60678 Go to UniProtKB: O60678 | |||||
PHAROS: O60678 GTEx: ENSG00000185238 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O60678 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SAH Query on SAH | B [auth A] | S-ADENOSYL-L-HOMOCYSTEINE C14 H20 N6 O5 S ZJUKTBDSGOFHSH-WFMPWKQPSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.246
- R-Value Work: 0.195
- R-Value Observed: 0.198
- Space Group: P 41 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 107.486 | α = 90 |
| b = 107.486 | β = 90 |
| c = 68.42 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2006-03-14 Deposition Author(s): Min, J.R., Wu, H., Zeng, H., Loppnau, P., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2006-03-14
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Advisory, Derived calculations, Version format compliance - Version 1.3: 2024-02-14
Changes: Data collection, Database references, Derived calculations
