Download MendeleyCrystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
Kavanagh, K.L., Johansson, C., Smee, C., Gileadi, O., von Delft, F., Oppermann, U.To be published.
2F8A
Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
- PDB DOI: https://doi.org/10.2210/pdb2F8A/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21
- Mutation(s): No
- Deposited: 2005-12-02 Released: 2005-12-13
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 Å
- R-Value Free: 0.156
- R-Value Work: 0.138
- R-Value Observed: 0.138
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Glutathione peroxidase 1 | 208 | Homo sapiens | Mutation(s): 0 Gene Names: GPX1 EC: 1.11.1.9 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P07203 (Homo sapiens) Explore P07203 Go to UniProtKB: P07203 | |||||
PHAROS: P07203 GTEx: ENSG00000233276 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P07203 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| MLA Query on MLA | C [auth A], D [auth B] | MALONIC ACID C3 H4 O4 OFOBLEOULBTSOW-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 Å
- R-Value Free: 0.156
- R-Value Work: 0.138
- R-Value Observed: 0.138
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 127.592 | α = 90 |
| b = 59.376 | β = 119.41 |
| c = 81.132 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| CCP4 | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2005-12-13 Deposition Author(s): Kavanagh, K.L., Johansson, C., Smee, C., Gileadi, O., von Delft, F., Weigelt, J., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2005-12-13
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Advisory, Version format compliance - Version 1.3: 2015-04-29
Changes: Non-polymer description - Version 1.4: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
