Download MendeleyCrystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from Plasmodium falciparum
Caruthers, J.M., Robein, M., Zucker, F., Mehlin, C., Luft, J., Boni, E., Lauricella, A., Merritt, E.A., Hol, W.G.J.To be published.
2F84
Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from P.falciparum
- PDB DOI: https://doi.org/10.2210/pdb2F84/pdb
- Classification: LYASE
- Organism(s): Plasmodium falciparum 3D7
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2005-12-01 Released: 2005-12-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.10 Å
- R-Value Free: 0.288
- R-Value Work: 0.227
- R-Value Observed: 0.230
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| orotidine monophosphate decarboxylase | 323 | Plasmodium falciparum 3D7 | Mutation(s): 0 Gene Names: NC_004314 EC: 4.1.1.23 |  | |
UniProt | |||||
Find proteins for Q8IJH3 (Plasmodium falciparum (isolate 3D7)) Explore Q8IJH3 Go to UniProtKB: Q8IJH3 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8IJH3 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PO4 Query on PO4 | B [auth A] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.10 Å
- R-Value Free: 0.288
- R-Value Work: 0.227
- R-Value Observed: 0.230
- Space Group: P 21 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 70.911 | α = 90 |
| b = 69.057 | β = 90 |
| c = 69.735 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SCALA | data scaling |
| EPMR | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| MOSFLM | data reduction |
| CCP4 | data scaling |
Entry History
Deposition Data
- Released Date: 2005-12-20 Deposition Author(s): Caruthers, J.M., Robein, M., Merritt, E.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Revision History (Full details and data files)
- Version 1.0: 2005-12-20
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Advisory, Derived calculations, Source and taxonomy, Version format compliance - Version 1.3: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
