Download MendeleyHuman UMP Synthase (C-terminal Domain - Orotidine 5'-Monophosphate Decarboxylase)
Liu, Y., Tang, H.L., Pai, E.F.To be published.
2EAW
Human UMP Synthase (C-terminal Domain- Orotidine 5'-Monophosphate Decarboxylase)
- PDB DOI: https://doi.org/10.2210/pdb2EAW/pdb
- Classification: LYASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2007-02-03 Released: 2007-02-13
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.88 Å
- R-Value Free: 0.307
- R-Value Work: 0.259
- R-Value Observed: 0.262
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Uridine 5'-monophosphate synthase | 291 | Homo sapiens | Mutation(s): 0 Gene Names: UMPS EC: 4.1.1.23 (PDB Primary Data), 2.4.2.10 (PDB Primary Data) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P11172 (Homo sapiens) Explore P11172 Go to UniProtKB: P11172 | |||||
PHAROS: P11172 GTEx: ENSG00000114491 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P11172 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | C [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.88 Å
- R-Value Free: 0.307
- R-Value Work: 0.259
- R-Value Observed: 0.262
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 67.571 | α = 90 |
| b = 59.37 | β = 114.3 |
| c = 69.863 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| PROTEUM PLUS | data collection |
| SAINT | data reduction |
| SADABS | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2007-02-13 Deposition Author(s): Liu, Y., Tang, H.L., Pai, E.F.
Revision History (Full details and data files)
- Version 1.0: 2007-02-13
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2023-10-25
Changes: Data collection, Database references, Derived calculations, Refinement description
