Download MendeleyStructure of the human FK-506 binding protein 8
Walker, J.R., Davis, T., Newman, E.M., Finerty, P., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S.To be published.
2AWG
Structure of the PPIase domain of the Human FK506-binding protein 8
- PDB DOI: https://doi.org/10.2210/pdb2AWG/pdb
- Classification: SIGNALING PROTEIN INHIBITOR
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2005-09-01 Released: 2005-09-27
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 Å
- R-Value Free: 0.202
- R-Value Work: 0.167
- R-Value Observed: 0.169
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 38 kDa FK-506 binding protein | 118 | Homo sapiens | Mutation(s): 0 Gene Names: FKBP8, FKBP38 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q14318 (Homo sapiens) Explore Q14318 Go to UniProtKB: Q14318 | |||||
PHAROS: Q14318 GTEx: ENSG00000105701 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q14318 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 Å
- R-Value Free: 0.202
- R-Value Work: 0.167
- R-Value Observed: 0.169
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 30.911 | α = 90 |
| b = 53.795 | β = 92.43 |
| c = 30.64 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| SCALEPACK | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2005-09-27 Deposition Author(s): Walker, J.R., Davis, T., Newman, E.M., Finerty, P., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2005-09-27
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2023-08-23
Changes: Data collection, Database references, Refinement description
