2AJD
Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro)
- PDB DOI: https://doi.org/10.2210/pdb2AJD/pdb
- Classification: HYDROLASE
- Organism(s): Sus scrofa
- Mutation(s): No 
- Deposited: 2005-08-01 Released: 2006-02-28 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.56 Å
- R-Value Free: 0.312 
- R-Value Work: 0.246 
This is version 2.1 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Dipeptidyl peptidase 4 | 728 | Sus scrofa | Mutation(s): 0  EC: 3.4.14.5 | ||
UniProt | |||||
Find proteins for P22411 (Sus scrofa) Explore P22411  Go to UniProtKB:  P22411 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P22411 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Small Molecules
Ligands 3 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NAG Query on NAG | AA [auth C] BA [auth C] CA [auth C] DA [auth C] GA [auth D] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N | |||
BPR Query on BPR | FA [auth C], JA [auth D], S [auth A], Y [auth B] | (2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE C9 H17 B N2 O3 XSBZZZGVAIXJLD-YUMQZZPRSA-N | |||
SO4 Query on SO4 | EA [auth C], IA [auth D], R [auth A], X [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.56 Å
- R-Value Free: 0.312 
- R-Value Work: 0.246 
- Space Group: P 1
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 63.4 | α = 111.41 |
b = 122.07 | β = 95.27 |
c = 134.03 | γ = 94.52 |
Software Name | Purpose |
---|---|
DENZO | data reduction |
SCALEPACK | data scaling |
CNS | refinement |
PDB_EXTRACT | data extraction |
CNS | phasing |
Entry History 
Deposition Data
- Released Date: 2006-02-28  Deposition Author(s): Engel, M., Hoffmann, T., Manhart, S., Heiser, U., Chambre, S., Huber, R., Demuth, H.U., Bode, W.
Revision History (Full details and data files)
- Version 1.0: 2006-02-28
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 1.3: 2017-10-11
Changes: Advisory, Refinement description - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Derived calculations, Structure summary - Version 2.1: 2023-08-23
Changes: Advisory, Data collection, Database references, Refinement description, Structure summary