Download MendeleyCrystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution
Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)To be published.
2A0S
Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution
- PDB DOI: https://doi.org/10.2210/pdb2A0S/pdb
- Classification: LYASE, BIOSYNTHETIC PROTEIN
- Organism(s): Plasmodium vivax
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2005-06-16 Released: 2005-07-26
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.246
- R-Value Work: 0.208
- R-Value Observed: 0.210
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 6-pyruvoyl tetrahydropterin synthase | 180 | Plasmodium vivax | Mutation(s): 0 Gene Names: MAL6P1.148 EC: 4.2.3.12 |  | |
UniProt | |||||
Find proteins for A5K2B2 (Plasmodium vivax (strain Salvador I)) Explore A5K2B2 Go to UniProtKB: A5K2B2 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A5K2B2 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| BIO Query on BIO | D [auth A], F [auth B] | BIOPTERIN C9 H11 N5 O3 LHQIJBMDNUYRAM-AWFVSMACSA-N |  | ||
| ZN Query on ZN | C [auth A], E [auth B] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.246
- R-Value Work: 0.208
- R-Value Observed: 0.210
- Space Group: H 3
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 132.095 | α = 90 |
| b = 132.095 | β = 90 |
| c = 74.126 | γ = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| CCP4 | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2005-07-26 Deposition Author(s): Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Revision History (Full details and data files)
- Version 1.0: 2005-07-26
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Advisory, Derived calculations, Version format compliance - Version 1.3: 2023-08-23
Changes: Data collection, Database references, Derived calculations, Refinement description
