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CRYSTAL STRUCTURE OF THE HIV-1 CAPSID PROTEIN C-TERMINAL DOMAIN IN COMPLEX WITH A CAMELID VHH AND THE CAI PEPTIDE.
2XXM
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System/peptide
    Structure Weight: 23195.21
    Molecule: CAPSID PROTEIN P24
    Polymer: 1 Type: protein Length: 75
    Chains: A
    Fragment: C-TERMINAL DOMAIN, RESIDUES 278-352
    Organism: Human immunodeficiency virus
    Gene Name: gag-pol
    UniProtKB: Protein Feature View | Search PDB | P12497  
    Molecule: CAMELID VHH 9
    Polymer: 2 Type: protein Length: 121
    Chains: B
    Organism: Vicugna pacos
    Molecule: INHIBITOR OF CAPSID ASSEMBLY
    Polymer: 3 Type: protein Length: 11
    Chains: T
    Organism: synthetic construct
     
  •   Structure Validation Hide

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  •   Source Hide
    Polymer: 1
    Scientific Name: Human immunodeficiency virus   Taxonomy   Common Name: Hiv-1 Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Vicugna pacos   Taxonomy   Common Name: Alpaca Expression System: Escherichia coli  
    Polymer: 3
    Scientific Name: Synthetic construct (synthetic construct)   Taxonomy    
     
  •   Related PDB Entries Hide
    Identifier Details
    1A43  STRUCTURE OF THE HIV-1 CAPSID PROTEIN DIMERIZATION DOMAINAT 2.6A RESOLUTION 
    1A8O  HIV CAPSID C-TERMINAL DOMAIN 
    1AFV  HIV-1 CAPSID PROTEIN (P24) COMPLEX WITH FAB25.3 
    1AK4  HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID 
    1AUM  HIV CAPSID C-TERMINAL DOMAIN (CAC146) 
    1B92  MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY 
    1B9D  MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY 
    1B9F  MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY 
    1BAJ  HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN 
    1BHL  CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE 
    1BI4  CATALYTIC DOMAIN OF HIV-1 INTEGRASE 
    1BIS  HIV-1 INTEGRASE CORE DOMAIN 
    1BIU  HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++ 
    1BIZ  HIV-1 INTEGRASE CORE DOMAIN 
    1BL3  CATALYTIC DOMAIN OF HIV-1 INTEGRASE 
    1GWP  STRUCTURE OF THE N-TERMINAL DOMAIN OF THE MATURE HIV -1 CAPSID PROTEIN 
    1HIW  TRIMERIC HIV-1 MATRIX PROTEIN 
    1ITG  HIV-1 INTEGRASE (CATALYTIC DOMAIN COMPRISING RESIDUES 50 - 212) MUTANT WITH GLY-SER-HIS APPENDED TO THE N- TERMINUS AND PHE 185 REPLACED BY LYS (INS(47-49), F185K) 
    1K6Y  CRYSTAL STRUCTURE OF A TWO-DOMAIN FRAGMENT OF HIV- 1INTEGRASE 
    1M9D  X-RAY CRYSTAL STRUCTURE OF CYCLOPHILIN A/HIV-1 CA N-TERMINAL DOMAIN (1-146) O-TYPE CHIMERA COMPLEX. 
    1QS4  CORE DOMAIN OF HIV-1 INTEGRASE COMLEXED WITH MG++ AND 1-(5- CHLOROINDOL-3-YL)-3-HYDROXY-3-(2H- TETRAZOL-5-YL)-PROPENONE 
    1UPH  HIV-1 MYRISTOYLATED MATRIX 
    1WJB  SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (D FORM), NMR, 40 STRUCTURES 
    1WJD  SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (E FORM), NMR, 38 STRUCTURES 
    1WKN  A PLAUSIBLE MODEL OF FULL-LENGTH INTEGRASEDNA COMPLEX 
    2B4J  STRUCTURAL BASIS FOR THE RECOGNITION BETWEEN HIV- 1INTEGRASE AND LEDGF/P75 
    2H3F  SOLUTION STRUCTURE OF THE HIV-1 MA PROTEIN 
    2H3I  SOLUTION STRUCTURE OF THE HIV-1 MYRISTOYLATED MATRIX PROTEIN 
    2H3Q  SOLUTION STRUCTURE OF HIV-1 MYRMA BOUND TO DI-C4- PHOSPHATIDYLINOSITOL-(4,5)-BISPHOSPHATE 
    2H3V  STRUCTURE OF THE HIV-1 MATRIX PROTEIN BOUND TO DI- C8-PHOSPHATIDYLINOSITOL-(4,5)-BISPHOSPHATE 
    2H3Z  STRUCTURE OF THE HIV-1 MATRIX PROTEIN BOUND TO DI- C4-PHOSPHATIDYLINOSITOL-(4,5)-BISPHOSPHATE 
    2HMX  HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 MATRIX PROTEIN 2HMX 3 
    2HVP  HIV-1 PROTEASE 
    2ITG  CATALYTIC DOMAIN OF HIV-1 INTEGRASE: ORDERED ACTIVE SITE IN THE F185H CONSTRUCT 
    2X2D  ACETYL-CYPA:HIV-1 N-TERM CAPSID DOMAIN COMPLEX 
    2XT1  CRYSTAL STRUCTURE OF THE HIV-1 CAPSID PROTEIN C- TERMINAL DOMAIN (146-231) IN COMPLEX WITH A CAMELID VHH. 
    2XV6  CRYSTAL STRUCTURE OF THE HIV-1 CAPSID PROTEIN C- TERMINAL DOMAIN (146-220) IN COMPLEX WITH A CAMELID VHH. 
    2XXC  CRYSTAL STRUCTURE OF A CAMELID VHH RAISED AGAINST THE HIV-1 CAPSID PROTEIN C-TERMINAL DOMAIN. 
    4PHV  HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) PROTEASE COMPLEX WITH N,N-BIS(2(R)-HYDROXY-1(S)-INDANYL)- 2,6-(R,R)- DIPHENYLMETHYL-4-HYDROXY-1,7- HEPTANDIAMIDE 
    5HVP  HIV-1 PROTEASE COMPLEX WITH ACETYL-PEPSTATIN (NY5 STRAIN) 
    9HVP  HIV-1 PROTEASE COMPLEX WITH A-74704 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    ACT
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    ACT C2 H3 O2
    ACETATE ION
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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