2VIS
INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
- PDB DOI: https://doi.org/10.2210/pdb2VIS/pdb
- Classification: COMPLEX (HEMAGGLUTININ/IMMUNOGLOBULIN)
- Organism(s): Mus musculus, Influenza A virus (A/X-31(H3N2))
- Mutation(s): Yes
- Deposited: 1997-12-22 Released: 1998-04-29
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.25 Å
- R-Value Free: 0.267
- R-Value Work: 0.188
- R-Value Observed: 0.188
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| IMMUNOGLOBULIN (IGG1, LAMBDA) | 210 | Mus musculus | Mutation(s): 0 |  | |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| IMMUNOGLOBULIN (IGG1, LAMBDA) | 221 | Mus musculus | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for Q99LC4 (Mus musculus) Explore Q99LC4 Go to UniProtKB: Q99LC4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q99LC4 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| HEMAGGLUTININ | 282 | Influenza A virus (A/X-31(H3N2)) | Mutation(s): 1 |  | |
UniProt | |||||
Find proteins for P03437 (Influenza A virus (strain A/Aichi/2/1968 H3N2)) Explore P03437 Go to UniProtKB: P03437 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P03437 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | F [auth C] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
| ZN Query on ZN | D [auth A], E [auth A], G [auth C] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.25 Å
- R-Value Free: 0.267
- R-Value Work: 0.188
- R-Value Observed: 0.188
- Space Group: P 61 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 85.5 | α = 90 |
| b = 85.5 | β = 90 |
| c = 515 | γ = 120 |
| Software Name | Purpose |
|---|---|
| HKL | data collection |
| X-PLOR | model building |
| X-PLOR | refinement |
| HKL | data reduction |
| X-PLOR | phasing |
Entry History
Deposition Data
- Released Date: 1998-04-29 Deposition Author(s): Bizebard, T., Fleury, D., Gigant, B., Wharton, S.A., Skehel, J.J., Knossow, M.
Revision History (Full details and data files)
- Version 1.0: 1998-04-29
Type: Initial release - Version 1.1: 2008-03-25
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 1.3: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Database references, Derived calculations, Other, Structure summary - Version 1.4: 2021-11-03
Changes: Database references, Structure summary
