Structural Analysis of the Unbound Form of HIV-1 Subtype C Protease
2R8N
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Hydrolase
    Structure Weight: 10936.09
    Molecule: Pol protein
    Polymer: 1 Type: protein Length: 99
    Chains: A
    EC#: 3.4.23.16   
    Fragment: HIV-1 protease subtype C, UNP residues 1-99
    Mutation: Q7K, L33I, L63I
    Organism: Human immunodeficiency virus 1
    Gene Name: gag-pol
    UniProtKB: Protein Feature View | Search PDB | O12158  
     
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  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Human immunodeficiency virus 1   Taxonomy   Expression System: Escherichia coli  
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    GOL
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    GOL C3 H8 O3
    GLYCEROL
     
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Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Coman, R.M.,  Robbins, A.H.,  McKenna, R.,  Dunn, B.M.

    Deposition:   2007-09-11
    Release:   2008-07-29
    Last Modified (REVDAT):   2011-07-13
     
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    2011-07-13
    Version format compliance
    2011-07-13
    Non-polymer description
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    Resolution[Å]:   1.20
    R-Value: 0.141 (obs.)
    R-Free: 0.178
    Space Group: P 41 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 46.71 α = 90.00 
    b = 46.71 β = 90.00 
    c = 100.71 γ = 90.00