2QWU

Crystal structure of F. tularensis pathogenicity island protein C

PDB DOI: https://doi.org/10.2210/pdb2QWU/pdb

Classification: CELL INVASION
Organism(s): Francisella tularensis subsp. tularensis
Expression System: Escherichia coli
Mutation(s): Yes

Deposited: 2007-08-10 Released: 2007-10-16
Deposition Author(s): Sun, P., Austin, B.P., Schubot, F.D., Waugh, D.S.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 1.65 Å
R-Value Free: 0.220
R-Value Work: 0.184
R-Value Observed: 0.184

wwPDB Validation 3D Report Full Report

This is version 1.3 of the entry. See complete history.

Literature

Crystal structure of Francisella tularensis pathogenicity island protein IglC

Sun, P., Austin, B.P., Schubot, F.D., Waugh, D.S.

To be published.

Macromolecule Content

Total Structure Weight: 45.83 kDa
Atom Count: 3,534
Modelled Residue Count: 414
Deposited Residue Count: 422
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Intracellular growth locus, subunit C	A, B	211	Francisella tularensis subsp. tularensis	Mutation(s): 2 Gene Names: iglC2, iglC1
UniProt
Find proteins for Q5NEC5 (Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)) Explore Q5NEC5 Go to UniProtKB: Q5NEC5
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q5NEC5
Sequence Annotations Expand
Reference Sequence

Small Molecules

Modified Residues 1 Unique
ID	Chains	Type	Formula	2D Diagram	Parent
MSE Query on MSE	A, B	L-PEPTIDE LINKING	C₅ H₁₁ N O₂ Se		MET

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 1.65 Å
R-Value Free: 0.220
R-Value Work: 0.184
R-Value Observed: 0.184
Space Group: P 2₁ 2₁ 2₁

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 49.031	α = 90
b = 83.991	β = 90
c = 89.838	γ = 90

Software Package:

Software Name	Purpose
HKL-2000	data collection
SGXPRO	model building
CNS	refinement
HKL-2000	data reduction
HKL-2000	data scaling
SGXPRO	phasing

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2007-10-16

Deposition Author(s):

Revision History (Full details and data files)

Version 1.0: 2007-10-16
Type: Initial release
Version 1.1: 2011-07-13
Changes: Version format compliance
Version 1.2: 2017-10-25
Changes: Refinement description
Version 1.3: 2021-10-20
Changes: Database references, Derived calculations

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.