2OZ4
Structural Plasticity in IgSF Domain 4 of ICAM-1 Mediates Cell Surface Dimerization
- PDB DOI: https://doi.org/10.2210/pdb2OZ4/pdb
- Classification: CELL ADHESION
- Organism(s): Homo sapiens, Mus musculus
- Expression System: Cricetulus griseus
- Mutation(s): No
- Deposited: 2007-02-23 Released: 2007-10-16
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 Å
- R-Value Free: 0.253
- R-Value Work: 0.204
- R-Value Observed: 0.209
This is version 2.1 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Intercellular adhesion molecule 1 | 265 | Homo sapiens | Mutation(s): 0 Gene Names: ICAM1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P05362 (Homo sapiens) Explore P05362 Go to UniProtKB: P05362 | |||||
PHAROS: P05362 GTEx: ENSG00000090339 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P05362 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| FAB FRAGMENT LIGHT CHAIN | B [auth L] | 214 | Mus musculus | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| FAB FRAGMENT, HEAVY CHAIN | C [auth H] | 214 | Mus musculus | Mutation(s): 0 |  |
UniProt | |||||
Find proteins for P01757 (Mus musculus) Explore P01757 Go to UniProtKB: P01757 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P01757 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | E [auth A], F [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
| TRS Query on TRS | K [auth L], L | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL C4 H12 N O3 LENZDBCJOHFCAS-UHFFFAOYSA-O |  | ||
| SO4 Query on SO4 | G [auth A], H [auth L] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| ZN Query on ZN | I [auth L], J [auth L] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 Å
- R-Value Free: 0.253
- R-Value Work: 0.204
- R-Value Observed: 0.209
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 185.396 | α = 90 |
| b = 69.342 | β = 112.76 |
| c = 88.173 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data collection |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2007-10-16 Deposition Author(s): Chen, X., Kim, T.D., Carman, C.V., Mi, L., Song, G., Springer, T.A.
Revision History (Full details and data files)
- Version 1.0: 2007-10-16
Type: Initial release - Version 1.1: 2011-07-13
Changes: Advisory, Version format compliance - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Derived calculations, Structure summary - Version 2.1: 2023-08-30
Changes: Data collection, Database references, Refinement description, Structure summary
