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Structure of HIV Protease NL4-3 in an Unliganded State
2HB4
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Hydrolase
    Structure Weight: 11084.49
    Molecule: Protease
    Polymer: 1 Type: protein Length: 99
    Chains: A
    EC#: 3.4.23.16   
    Fragment: residues 500-598
    Mutation: Q7K
    Organism: Human immunodeficiency virus 1
    UniProtKB: Protein Feature View | Search PDB | Q903N5  
     
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  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Human immunodeficiency virus 1   Taxonomy   Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    2AZ8  Structure of wild-type HIV protease in complex with TL-3. 
    2HB2  Structure of HIV protease 6X mutant in unliganded state. 
    2HC0   
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    MG
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    MG Mg
    MAGNESIUM ION
    PGR
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    PGR C3 H8 O2
    R-1,2-PROPANEDIOL
     
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  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA,PQS (software)
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  •   Deposition Summary Hide
    Authors:   Heaslet, H.,  Tam, K.,  Elder, J.H.,  Stout, C.D.

    Deposition:   2006-06-13
    Release:   2007-06-26
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
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    2011-07-13
    Biological assembly
    2011-07-13
    Flag residual B-value
    2011-07-13
    Version format compliance
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.15
    R-Value: 0.238 (obs.)
    R-Free: 0.321
    Space Group: P 41 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 48.99 α = 90.00 
    b = 48.99 β = 90.00 
    c = 105.62 γ = 90.00