Download MendeleyThe crystal structure of human Rab27b
Wang, J., Ismail, S., Shen, Y., Tempel, W., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Bochkarev, A., Park, H.W.To be published.
2F7S
The crystal structure of human Rab27b bound to GDP
- PDB DOI: https://doi.org/10.2210/pdb2F7S/pdb
- Classification: SIGNALING PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2005-12-01 Released: 2005-12-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 Å
- R-Value Free: 0.292
- R-Value Work: 0.245
- R-Value Observed: 0.248
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Ras-related protein Rab-27B | 217 | Homo sapiens | Mutation(s): 0 Gene Names: RAB27B |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O00194 (Homo sapiens) Explore O00194 Go to UniProtKB: O00194 | |||||
PHAROS: O00194 GTEx: ENSG00000041353 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O00194 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GDP Query on GDP | D [auth A], F [auth B] | GUANOSINE-5'-DIPHOSPHATE C10 H15 N5 O11 P2 QGWNDRXFNXRZMB-UUOKFMHZSA-N |  | ||
| MG Query on MG | C [auth A], E [auth B] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 Å
- R-Value Free: 0.292
- R-Value Work: 0.245
- R-Value Observed: 0.248
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 55.469 | α = 90 |
| b = 64.023 | β = 90 |
| c = 153.32 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| SCALEPACK | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2005-12-20 Deposition Author(s): Wang, J., Ismail, S., Shen, Y., Tempel, W., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Bochkarev, A., Park, H.W., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2005-12-20
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
