Download Mendeleyprobing the roles of active site residues in 3'-5' exonuclease of werner syndrome protein
Cho, Y., Choi, J.M.To be published.
2E6M
structure of mouse werner exonuclease domain
- PDB DOI: https://doi.org/10.2210/pdb2E6M/pdb
- Classification: HYDROLASE
- Organism(s): Mus musculus
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2006-12-27 Released: 2007-01-16
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.243
- R-Value Work: 0.209
- R-Value Observed: 0.209
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Werner syndrome ATP-dependent helicase homolog | 208 | Mus musculus | Mutation(s): 0 Gene Names: Wrn EC: 3.6.1 |  | |
UniProt | |||||
Find proteins for O09053 (Mus musculus) Explore O09053 Go to UniProtKB: O09053 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O09053 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | B [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.243
- R-Value Work: 0.209
- R-Value Observed: 0.209
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 54.925 | α = 90 |
| b = 59.189 | β = 90 |
| c = 60.466 | γ = 90 |
| Software Name | Purpose |
|---|---|
| CNS | refinement |
| HKL-2000 | data collection |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| CNS | phasing |
Entry History
Deposition Data
- Released Date: 2007-01-16 Deposition Author(s): Cho, Y., Choi, J.M.
Revision History (Full details and data files)
- Version 1.0: 2007-01-16
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2023-10-25
Changes: Data collection, Database references, Derived calculations, Refinement description
