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HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455
2BQV
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Hydrolase/inhibitor
    Structure Weight: 22196.30
    Molecule: HIV-1 PROTEASE
    Polymer: 1 Type: protein Length: 99
    Chains: A, B
    EC#: 3.4.23.16   
    Details: COMPLEX WITH INHIBITOR AHA455
    Organism: Human immunodeficiency virus 1
    Gene Name: pol
    UniProtKB: Protein Feature View | Search PDB | O92139  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Human immunodeficiency virus 1   Taxonomy   Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    1HVC  HIV-1 PROTEASE (TETHERED DIMER LINKED BY GLY-GLY-SER-SER-GLY) COMPLEXED WITH A- 76928 
    2BB9  STRUCTURE OF HIV1 PROTEASE AND AKC4P_133A COMPLEX. 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    A1A
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    A1A C33 H40 N4 O6
    6-AMINO HEXANOIC ACID
    A1A:2BQV
     
  •   External Ligand Annotations Hide
    Identifier   Binding Affinity (Sequence Identity %)
    A1A
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    A1A
    Ki: 9 nM (98) - data from BindingDB  
    Ki: 9 nM - data from BindingMOAD  
    N/Ain PDBbind
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PQS (software)
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