Structure of HIV-1 protease mutant bound to indinavir     DOI:10.2210/pdb2b7z/pdb

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Primary Citation       Molecular Description Hide Classification: Viral Protein Structure Weight: 22277.40   Molecule: HIV-1 protease Polymer: 1 Type: polypeptide(L) Length: 99 Chains: A, B Mutation: K20R, V32I, L33F, M36I, M46I, L63P, A71V, V82A, I84V, L90M       Source Hide Polymer: 1 Scientific Name: Human immunodeficiency virus 1 Expression System: Escherichia coli         Related PDB Entries Hide Id Details 2B60          Ligand Chemical Component Hide Identifier Name Formula Interaction View Links MK1     N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)- 4(3 -PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY- 2(R)-PHENYLMETHYLPENTANAMIDE C36 H47 N5 O4 Ligand Explorer       Derived Data Hide CATH Classification v3.2.0 - (2 Domains) PFAM Classification - (2 Domains) GO Terms - (34 Terms)     Reset Layout

Biological Assembly     More Images... View in Jmol Other Viewers close KiNG WebMol QuickPDB FirstGlance Kiosk SimpleViewer Protein Workshop Ligand Explorer Biological assembly assigned by authors         Deposition Summary Hide Authors:   Clemente, J.C.,   Stow, L.R.,   Janka, L.K.,   Jeung, J.A.,   Desai, K.A.,   Govindasamy, L.,   Agbandje-McKenna, M.,   McKenna, R.,   Goodenow, M.M.,   Dunn, B.M. Deposition:   2005-10-05 Release:   2006-11-14 Last Modified (REVDAT):   2009-02-24       Experimental Details Hide Method:   X-RAY DIFFRACTION Experimental Data:    [ EDS ] Resolution[Å]: 2.20 R-Value: 0.209 (obs.) R-Free: 0.254 Space Group: P 61 Unit Cell:   Length [Å] Angles [°] a = 61.83 α = 90.00  b = 61.83 β = 90.00  c = 84.03 γ = 120.00        Structure Links Hide Molecule of the Month Features: HIV-1 Protease