Download MendeleyCrystal structure of a human malic enzyme
Papagrigoriou, E., Berridge, G., Smee, C., Bray, J., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Gileadi, O., von Delft, F.To be published.
2AW5
Crystal structure of a human malic enzyme
- PDB DOI: https://doi.org/10.2210/pdb2AW5/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2005-08-31 Released: 2005-09-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.256
- R-Value Work: 0.207
- R-Value Observed: 0.210
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| NADP-dependent malic enzyme | 575 | Homo sapiens | Mutation(s): 0 EC: 1.1.1.40 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P48163 (Homo sapiens) Explore P48163 Go to UniProtKB: P48163 | |||||
PHAROS: P48163 GTEx: ENSG00000065833 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P48163 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.256
- R-Value Work: 0.207
- R-Value Observed: 0.210
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 152.505 | α = 90 |
| b = 136.963 | β = 121.75 |
| c = 117.84 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| CCP4 | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2005-09-20 Deposition Author(s): Papagrigoriou, E., Berridge, G., Smee, C., Bray, J., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Gileadi, O., von Delft, F., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2005-09-20
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2024-03-13
Changes: Data collection, Database references, Refinement description
