Download MendeleyCrystal Structure Analysis of Human liver GAPDH
Ismail, S.A., Park, H.W.To be published.
1ZNQ
Crystal Structure of Human Liver GAPDH
- PDB DOI: https://doi.org/10.2210/pdb1ZNQ/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2005-05-11 Released: 2005-05-24
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.229
- R-Value Work: 0.211
This is version 1.5 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Glyceraldehyde-3-phosphate dehydrogenase, liver | A [auth O], B [auth P], C [auth R], D [auth Q] | 338 | Homo sapiens | Mutation(s): 0 Gene Names: GAPD EC: 1.2.1.12 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P04406 (Homo sapiens) Explore P04406 Go to UniProtKB: P04406 | |||||
PHAROS: P04406 GTEx: ENSG00000111640 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P04406 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAD Query on NAD | E [auth O], F [auth P], G [auth R], H [auth Q] | NICOTINAMIDE-ADENINE-DINUCLEOTIDE C21 H27 N7 O14 P2 BAWFJGJZGIEFAR-NNYOXOHSSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.229
- R-Value Work: 0.211
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 124.5 | α = 90 |
| b = 132.31 | β = 90 |
| c = 86.037 | γ = 90 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data collection |
| SCALEPACK | data scaling |
| AMoRE | phasing |
| CNS | refinement |
| HKL-2000 | data reduction |
Entry History
Deposition Data
- Released Date: 2005-05-24 Deposition Author(s): Ismail, S.A., Park, H.W.
Revision History (Full details and data files)
- Version 1.0: 2005-05-24
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2014-11-12
Changes: Structure summary - Version 1.4: 2019-01-16
Changes: Data collection, Structure summary - Version 1.5: 2023-08-23
Changes: Data collection, Database references, Derived calculations, Refinement description
