Download MendeleyCrystallographic structure of plasmid-encoded CMY-2 beta-lactamase revealed citrate molecule in the active site.
Bauvois, C., Jacquamet, L., Fieulaine, S., Frere, J.-M., Galleni, M., Ferrer, J.-L.To be published.
1ZC2
Crystal Structure of plasmid-encoded class C beta-lactamase CMY-2 complexed with citrate molecule
- PDB DOI: https://doi.org/10.2210/pdb1ZC2/pdb
- Classification: HYDROLASE
- Organism(s): Klebsiella pneumoniae
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2005-04-10 Released: 2006-04-25
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.09 Å
- R-Value Free: 0.299
- R-Value Work: 0.225
- R-Value Observed: 0.228
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| beta-lactamase class C | 361 | Klebsiella pneumoniae | Mutation(s): 0 Gene Names: bla CMY-2 EC: 3.5.2.6 |  | |
UniProt | |||||
Find proteins for Q48434 (Klebsiella pneumoniae) Explore Q48434 Go to UniProtKB: Q48434 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q48434 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| CIT Query on CIT | C [auth A], D [auth B] | CITRIC ACID C6 H8 O7 KRKNYBCHXYNGOX-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.09 Å
- R-Value Free: 0.299
- R-Value Work: 0.225
- R-Value Observed: 0.228
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 72.71 | α = 90 |
| b = 97.1 | β = 90 |
| c = 103.31 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| XDS | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2006-04-25 Deposition Author(s): Bauvois, C., Jacquamet, L., Fieulaine, S., Frere, J.-M., Galleni, M., Ferrer, J.-L.
Revision History (Full details and data files)
- Version 1.0: 2006-04-25
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2024-03-13
Changes: Data collection, Database references, Derived calculations
