1Z9X

Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 3 monomers in the asymmetric unit


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.93 Å
  • R-Value Free: 0.351 
  • R-Value Work: 0.328 
  • R-Value Observed: 0.330 

wwPDB Validation   3D Report Full Report


This is version 1.5 of the entry. See complete history


Literature

A structural insight into the double-locking mechanism of the human death-associated DRP-1 kinase

Kursula, P.Lehmann, F.Shani, G.Kimchi, A.Wilmanns, M.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Death-associated protein kinase 2
A, B, C
321Homo sapiensMutation(s): 4 
Gene Names: DAPK2
EC: 2.7.1.37
UniProt & NIH Common Fund Data Resources
Find proteins for Q9UIK4 (Homo sapiens)
Explore Q9UIK4 
Go to UniProtKB:  Q9UIK4
PHAROS:  Q9UIK4
GTEx:  ENSG00000035664 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ9UIK4
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.93 Å
  • R-Value Free: 0.351 
  • R-Value Work: 0.328 
  • R-Value Observed: 0.330 
  • Space Group: C 1 2 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 126.4α = 90
b = 62.99β = 110.98
c = 150.97γ = 90
Software Package:
Software NamePurpose
REFMACrefinement
MAR345data collection
XDSdata scaling
AMoREphasing

Structure Validation

View Full Validation Report



Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2006-10-24
    Type: Initial release
  • Version 1.1: 2008-04-30
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Advisory, Version format compliance
  • Version 1.3: 2017-10-11
    Changes: Refinement description
  • Version 1.4: 2021-10-20
    Changes: Data collection, Database references
  • Version 1.5: 2023-08-23
    Changes: Data collection, Refinement description