Download MendeleyStructural Analysis of Plasmodium falciparum 6-pyruvoyl tetrahydropterin synthase (PTPS)
Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)To be published.
1Y13
Structural Analysis of Plasmodium falciparum 6-pyruvoyl tetrahydropterin synthase (PTPS)
- PDB DOI: https://doi.org/10.2210/pdb1Y13/pdb
- Classification: LYASE, BIOSYNTHETIC PROTEIN
- Organism(s): Plasmodium falciparum
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2004-11-17 Released: 2005-01-04
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.235
- R-Value Work: 0.195
- R-Value Observed: 0.197
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 6-pyruvoyl tetrahydropterin synthase | 181 | Plasmodium falciparum | Mutation(s): 1 EC: 4.2.3.12 |  | |
UniProt | |||||
Find proteins for C6KTB6 (Plasmodium falciparum (isolate 3D7)) Explore C6KTB6 Go to UniProtKB: C6KTB6 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | C6KTB6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| BIO Query on BIO | E [auth A], G [auth B], I [auth C] | BIOPTERIN C9 H11 N5 O3 LHQIJBMDNUYRAM-AWFVSMACSA-N |  | ||
| ZN Query on ZN | D [auth A], F [auth B], H [auth C] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MSE Query on MSE | A, B, C | L-PEPTIDE LINKING | C5 H11 N O2 Se |  | MET |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.235
- R-Value Work: 0.195
- R-Value Observed: 0.197
- Space Group: P 43 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 103.319 | α = 90 |
| b = 103.319 | β = 90 |
| c = 131.111 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| CCP4 | data scaling |
| SOLVE | phasing |
Entry History
Deposition Data
- Released Date: 2005-01-04 Deposition Author(s): Bosch, J., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Revision History (Full details and data files)
- Version 1.0: 2005-01-04
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Advisory, Derived calculations, Refinement description, Version format compliance
