1WT3
Mutant human ABO(H) blood group glycosyltransferase with bound UDP and acceptor
- PDB DOI: https://doi.org/10.2210/pdb1WT3/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes 
- Deposited: 2004-11-12 Released: 2004-12-03 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.232 
- R-Value Work: 0.203 
- R-Value Observed: 0.228 
This is version 2.1 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Histo-blood group ABO system transferase | 292 | Homo sapiens | Mutation(s): 2  EC: 2.4.1.40 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P16442 (Homo sapiens) Explore P16442  Go to UniProtKB:  P16442 | |||||
PHAROS:  P16442 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P16442 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Small Molecules
Ligands 2 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
UDP Query on UDP | G [auth A] | URIDINE-5'-DIPHOSPHATE C9 H14 N2 O12 P2 XCCTYIAWTASOJW-XVFCMESISA-N | |||
HG Query on HG | C [auth A], D [auth A], E [auth A], F [auth A] | MERCURY (II) ION Hg BQPIGGFYSBELGY-UHFFFAOYSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 Å
- R-Value Free: 0.232 
- R-Value Work: 0.203 
- R-Value Observed: 0.228 
- Space Group: C 2 2 21
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 52.6 | α = 90 |
b = 149.1 | β = 90 |
c = 79.1 | γ = 90 |
Entry History 
Deposition Data
- Released Date: 2004-12-03  Deposition Author(s): Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M.
Revision History (Full details and data files)
- Version 1.0: 2004-12-03
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Derived calculations, Version format compliance - Version 1.3: 2012-06-20
Changes: Structure summary - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary - Version 2.1: 2024-03-13
Changes: Data collection, Database references, Structure summary