1WAR
Recombinant Human Purple Acid Phosphatase expressed in Pichia Pastoris
- PDB DOI: https://doi.org/10.2210/pdb1WAR/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Komagataella pastoris
- Mutation(s): No 
- Deposited: 2004-10-28 Released: 2005-07-06 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.22 Å
- R-Value Free: 0.198 
- R-Value Work: 0.138 
- R-Value Observed: 0.141 
This is version 1.4 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
HUMAN PURPLE ACID PHOSPHATASE | 310 | Homo sapiens | Mutation(s): 0  EC: 3.1.3.2 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P13686 (Homo sapiens) Explore P13686  Go to UniProtKB:  P13686 | |||||
PHAROS:  P13686 GTEx:  ENSG00000102575  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P13686 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
Ligands 3 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NAG Query on NAG | E [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N | |||
PO4 Query on PO4 | D [auth A] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K | |||
FE Query on FE | B [auth A], C [auth A] | FE (III) ION Fe VTLYFUHAOXGGBS-UHFFFAOYSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.22 Å
- R-Value Free: 0.198 
- R-Value Work: 0.138 
- R-Value Observed: 0.141 
- Space Group: P 43 21 2
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 80.538 | α = 90 |
b = 80.538 | β = 90 |
c = 99.998 | γ = 90 |
Software Name | Purpose |
---|---|
REFMAC | refinement |
DENZO | data reduction |
SCALEPACK | data scaling |
MOLREP | phasing |
Entry History 
Deposition Data
- Released Date: 2005-07-06  Deposition Author(s): Duff, A.P., Langley, D.B., Han, R., Averill, B.A., Freeman, H.C., Guss, J.M.
Revision History (Full details and data files)
- Version 1.0: 2005-07-06
Type: Initial release - Version 1.1: 2011-07-13
Changes: Advisory, Refinement description, Version format compliance - Version 1.2: 2019-04-03
Changes: Data collection, Derived calculations, Experimental preparation, Other - Version 1.3: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Derived calculations, Other, Structure summary - Version 1.4: 2023-12-13
Changes: Data collection, Database references, Refinement description, Structure summary