Download MendeleyCrystal Structure of the Pleckstrin Homology Domain of Pepp1
Milburn, C.C., Komander, D., Deak, M., Alessi, D.R., Van Aalten, D.M.F.To be published.
1UPQ
Crystal structure of the pleckstrin homology (PH) domain of PEPP1
- PDB DOI: https://doi.org/10.2210/pdb1UPQ/pdb
- Classification: SIGNAL TRANSDUCTION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21
- Mutation(s): No
- Deposited: 2003-10-09 Released: 2004-10-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.48 Å
- R-Value Free: 0.243
- R-Value Observed: 0.181
wwPDB Validation 3D Report Full Report
This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| PEPP1 | 123 | Homo sapiens | Mutation(s): 0 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9H4M7 (Homo sapiens) Explore Q9H4M7 Go to UniProtKB: Q9H4M7 | |||||
PHAROS: Q9H4M7 GTEx: ENSG00000105559 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9H4M7 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | B [auth A], C [auth A], D [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.48 Å
- R-Value Free: 0.243
- R-Value Observed: 0.181
- Space Group: P 4 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 93.547 | α = 90 |
| b = 93.547 | β = 90 |
| c = 28.786 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SHELXL-97 | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| SHELX | phasing |
Entry History
Deposition Data
- Released Date: 2004-10-07 Deposition Author(s): Milburn, C.C., Komander, D., Deak, M., Alessi, D.R., van Aalten, D.M.F.
Revision History (Full details and data files)
- Version 1.0: 2004-10-07
Type: Initial release - Version 1.1: 2011-05-08
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2018-02-28
Changes: Source and taxonomy, Structure summary - Version 1.4: 2019-05-22
Changes: Data collection, Refinement description - Version 1.5: 2023-12-13
Changes: Data collection, Database references, Other, Refinement description
