1SO0
Crystal structure of human galactose mutarotase complexed with galactose
- PDB DOI: https://doi.org/10.2210/pdb1SO0/pdb
- Classification: ISOMERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2004-03-12 Released: 2004-03-30
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.198
- R-Value Work: 0.167
- R-Value Observed: 0.169
This is version 1.5 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| aldose 1-epimerase | 344 | Homo sapiens | Mutation(s): 0 Gene Names: GALM EC: 5.1.3.3 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q96C23 (Homo sapiens) Explore Q96C23 Go to UniProtKB: Q96C23 | |||||
PHAROS: Q96C23 GTEx: ENSG00000143891 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q96C23 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GAL Query on GAL | E [auth A], F [auth B], G [auth C], H [auth D] | beta-D-galactopyranose C6 H12 O6 WQZGKKKJIJFFOK-FPRJBGLDSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.198
- R-Value Work: 0.167
- R-Value Observed: 0.169
- Space Group: P 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 61 | α = 107.7 |
| b = 68.7 | β = 98.4 |
| c = 98.9 | γ = 102.7 |
| Software Name | Purpose |
|---|---|
| FRAMBO | data collection |
| SAINT | data reduction |
| AMoRE | phasing |
| TNT | refinement |
| SAINT | data scaling |
Entry History
Deposition Data
- Released Date: 2004-03-30 Deposition Author(s): Thoden, J.B., Timson, D.J., Reece, R.J., Holden, H.M.
Revision History (Full details and data files)
- Version 1.0: 2004-03-30
Type: Initial release - Version 1.1: 2008-04-29
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2017-10-11
Changes: Refinement description - Version 1.4: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Database references, Derived calculations, Structure summary - Version 1.5: 2023-08-23
Changes: Data collection, Database references, Refinement description, Structure summary
