HLA-DR1 complexed with a 16 residue HIV capsid peptide bound in a hairpin conformation
1SJE
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System
    Structure Weight: 72361.78
    Molecule: HLA class II histocompatibility antigen, DR alpha chain
    Polymer: 1 Type: protein Length: 180
    Chains: A
    Fragment: Extracelluar domain of HLA-DRA*0101
    Organism: Homo sapiens
    Gene Names: Gene View for HLA-DRA HLA-DRA1
    UniProtKB: Protein Feature View | Search PDB | P01903  
    Molecule: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Polymer: 2 Type: protein Length: 190
    Chains: B
    Fragment: Extracelluar domain of HLA-DRB*0101
    Organism: Homo sapiens
    Gene Name: Gene View for HLA-DRB1
    UniProtKB: Protein Feature View | Search PDB | P04229  
    Molecule: GAG polyprotein
    Polymer: 3 Type: protein Length: 16
    Chains: C
    Fragment: 16 residue Peptide from HIV-1 gag capsid protein
    Organism: Human immunodeficiency virus type 1 (Z2/CDC-Z34 ISOLATE)
    Gene Name: gag
    UniProtKB: Protein Feature View | Search PDB | P12495  
    Molecule: Enterotoxin type C-3
    Polymer: 4 Type: protein Length: 239
    Chains: D
    Fragment: SEC3 variant 3B2
    Mutation: K43S,L45F,A46K,H47W
    Organism: Staphylococcus aureus
    Gene Name: entC3
    UniProtKB: Protein Feature View | Search PDB | P0A0L5  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
    Polymer: 3
    Scientific Name: Synthetic construct (Human immunodeficiency virus type 1 (Z2/CDC-Z34 ISOLATE))   Taxonomy    
    Polymer: 4
    Scientific Name: Staphylococcus aureus   Taxonomy   Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    1KLU   HLA-DR1/TPI/SEC3-3B2, similar to current entry but with a different peptide bound to HLA-DR1 
    1PYW   HLA-DR1/FVKQNA*AAL/SEC3-3B2 (*A is N-methyl alanine), similar to current entry but with a different peptide bound to HLA-DR1 
    1SJH   HLA-DR1 complexed with a 13 residue HIV capsid peptide 
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors
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