1S9K

Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.10 Å
  • R-Value Free: 0.275 
  • R-Value Work: 0.242 
  • R-Value Observed: 0.242 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history


Literature

Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site

Wang, D.Stroud, J.C.Chen, L.

To be published.

Macromolecules

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Entity ID: 3
MoleculeChains Sequence LengthOrganismDetailsImage
Nuclear factor of activated T-cells, cytoplasmic 2280Homo sapiensMutation(s): 0 
Gene Names: NFATC2NFAT1NFATP
UniProt & NIH Common Fund Data Resources
Find proteins for Q13469 (Homo sapiens)
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Go to UniProtKB:  Q13469
PHAROS:  Q13469
GTEx:  ENSG00000101096 
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UniProt GroupQ13469
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Entity ID: 4
MoleculeChains Sequence LengthOrganismDetailsImage
Proto-oncogene protein c-fos53Homo sapiensMutation(s): 0 
Gene Names: FOSG0S7
UniProt & NIH Common Fund Data Resources
Find proteins for P01100 (Homo sapiens)
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Go to UniProtKB:  P01100
PHAROS:  P01100
GTEx:  ENSG00000170345 
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UniProt GroupP01100
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Entity ID: 5
MoleculeChains Sequence LengthOrganismDetailsImage
Transcription factor AP-152Homo sapiensMutation(s): 0 
Gene Names: JUN
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Find proteins for P05412 (Homo sapiens)
Explore P05412 
Go to UniProtKB:  P05412
PHAROS:  P05412
GTEx:  ENSG00000177606 
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UniProt GroupP05412
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Entity ID: 1
MoleculeChains LengthOrganismImage
Human IL-2 ARRE1 Promoter Element, Plus Strand20N/A
Sequence Annotations
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Entity ID: 2
MoleculeChains LengthOrganismImage
Human IL-2 ARRE1 Promoter Element, Minus Strand20N/A
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.10 Å
  • R-Value Free: 0.275 
  • R-Value Work: 0.242 
  • R-Value Observed: 0.242 
  • Space Group: P 1 21 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 64.769α = 90
b = 86.26β = 111.24
c = 84.044γ = 90
Software Package:
Software NamePurpose
DENZOdata reduction
SCALEPACKdata scaling
CNSrefinement
CNSphasing

Structure Validation

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Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2005-06-14
    Type: Initial release
  • Version 1.1: 2008-04-29
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Version format compliance
  • Version 1.3: 2024-02-14
    Changes: Data collection, Database references