1R54
Crystal structure of the catalytic domain of human ADAM33
- PDB DOI: https://doi.org/10.2210/pdb1R54/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Drosophila melanogaster
- Mutation(s): Yes
- Deposited: 2003-10-09 Released: 2004-10-12
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.85 Å
- R-Value Free: 0.233
- R-Value Work: 0.208
- R-Value Observed: 0.209
wwPDB Validation 3D Report Full Report
This is version 2.1 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| ADAM 33 | 214 | Homo sapiens | Mutation(s): 1 Gene Names: ADAM33 EC: 3.4.24 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9BZ11 (Homo sapiens) Explore Q9BZ11 Go to UniProtKB: Q9BZ11 | |||||
PHAROS: Q9BZ11 GTEx: ENSG00000149451 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9BZ11 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Oligosaccharides
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZN Query on ZN | C [auth A] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
| CA Query on CA | D [auth A] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
| CL Query on CL | E [auth A], F [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.85 Å
- R-Value Free: 0.233
- R-Value Work: 0.208
- R-Value Observed: 0.209
- Space Group: C 2 2 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 56.476 | α = 90 |
| b = 65.461 | β = 90 |
| c = 99.863 | γ = 90 |
| Software Name | Purpose |
|---|---|
| MAR345 | data collection |
| SCALEPACK | data scaling |
| AMoRE | phasing |
| CNS | refinement |
Entry History
Deposition Data
- Released Date: 2004-10-12 Deposition Author(s): Orth, P., Reicher, P., Wang, W., Prosise, W.W., Yarosh-Tomaine, T., Hammond, G., Xiao, L., Mirza, U.A., Zou, J., Strickland, C., Taremi, S.S.
Revision History (Full details and data files)
- Version 1.0: 2004-10-12
Type: Initial release - Version 1.1: 2008-04-29
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 1.3: 2011-11-16
Changes: Atomic model - Version 1.4: 2017-10-11
Changes: Refinement description - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary - Version 2.1: 2021-10-27
Changes: Database references, Structure summary
